Tecnologias alternativas de criação de conteúdos para ambientes Fulldome

Mestrado em Comunicação Multimédia - Audiovisual DigitalO Fulldome, também conhecido como cinema imersivo, surgiu a partir da evolução de diversos media analógicos e digitais, dentre os quais podemos destacar os panoramas, os dispositivos de realidade virtual e os planetários. Trata-se de um modo de projecção onde os conteúdos são projectados numa tela esférica que preenche todo o ângulo de visão do espectador criando a sensação de imersão no ambiente apresentado. Foi a partir do final do século passado que os conteúdos para ambientes Fulldome começaram a ser criados. Devido a sua origem estar ligada aos planetários, a maioria das produções desenvolvidas para Fulldome são documentários científicos ou educacionais relativos à astronomia, criados a partir de softwares de animação em 3D. Pouco foi desenvolvido a partir da captação de imagens reais, utilizando-se câmaras de vídeo ou fotográficas. A presente dissertação propõe-se a apresentar ferramentas tecnológicas alternativas àquelas que são comummente utilizadas na criação de conteúdos para ambientes Fulldome. Objectiva-se aqui pesquisar e apresentar tecnologias capazes de suprir as exigências técnicas que as imagens destinadas aos ambientes imersivos necessitam para uma boa representação quando projectadas no ecrã hemisférico. Pretende-se com este estudo contribuir para a popularização entre os produtores audiovisuais sobre a criação de conteúdos para ambientes Fulldome. ABSTRACT: Fulldome, also known as immersive cinema, is part of the evolution of different analogical and digital media, from which we can pick out panoramas, virtual reality devices and planetariums. It’s a way of projecting through which contents are projected into a spherical screen covering entire viewer’s field of view, creating a feeling of total immersion in the presented environment. Contents for Fulldome environments started being developed at the end of the last century. Because their origin is connected with planetariums, most Fulldome productions are scientific or educational documentaries, created from 3D animation software, most dealing with astronomy. Thus, the capture of real image, using video or photo cameras was not very developed. This presentation aims at presenting technological tools that offer an alternative to those more commonly used when creating Fulldome contents. The main goals are to research and introduce technologies that are able to answer the technical demands of images used in immersive environments in order to have a good representation in hemispheric screens. With this study we intend to support the creation of contents for Fulldome environments among audiovisual producers

Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration

Evidence that otoliths, mineral-rich limestone concrescences present in the inner ear of bone fishes, can accelerate bone formation in vivo has been previously reported. The goal of this work was the development, characterization, and evaluation of the cytocompatibility of otoliths-incorporated sodium alginate and gelatin scaffolds. Cynoscion acoupaderived otoliths were characterized by X-ray fluorescence spectrometry (FRX), particle size, free lime, and weight loss by calcination. Furthermore, otoliths were incorporated into sodium alginate (ALG/OTL-s) or gelatin (GEL/OTL-s) scaffolds, previously developed by freeze-drying. Then, the scaffolds were characterized by thermogravimetric analysis (TGA/DTG), differential scanning calorimetry (DSC), infrared spectroscopy with Fourier transform (FTIR), swelling tests, and scanning electron microscopy (SEM). Cytotoxicity assays were run against J774.G8 macrophages and MC3T3-E1 osteoblasts. Data obtained from TGA/DTG, DSC, and FTIR analyses confirmed the interaction between otoliths and the polymeric scaffolds. SEM showed the homogeneous porous 3D structure rich in otolith micro-fragments in both scaffolds. Swelling of the GEL/OTL-s (63.54±3.0%) was greater than of ALG/OTL-s (13.36±9.9%) (p0.05) and significantly higher than that treated with Triton-X (p0.05). However, by 48 h, only ALG/OTL-s showed growth similar to control (p>0.05), whereas GEL/OTL showed a significantly lower growth index (p<0.05). In conclusion, the physicochemical profiles suggest proper interaction between the otoliths and the two developed polymeric 3D scaffolds. Moreover, both materials showed cytocompatibility with J774.G8 macrophages but the growth of MC3T3-E1 osteoblasts was higher when exposed to ALG/OTL-s. These data suggest that sodium alginate/otoliths scaffolds are potential biomaterials to be used in bone regeneration applications.We would like to thank the National Council for Scientific and Technological Development (CNPq) and the Foundation for Research and Technological Innovation Support of the State of Sergipe for the financial support in this study. EMBS acknowledges the sponsorship of the projects M-ERA-NET-0004/2015-PAIRED and UIDB/04469/2020 (strategic fund), received support from the Portuguese Science and Technology Foundation, Ministry of Science and Education (FCT/MEC) through national funds, and was co-financed by FEDER, under the Partnership Agreement PT2020.info:eu-repo/semantics/publishedVersio

Correlations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients- A Clinical Perspective Study

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Molecular epidemiological studies have identified several risk factors linking to the genes and external factors in the pathogenesis of breast cancer. In this sense, genetic instability caused by DNA damage and DNA repair inefficiencies are important molecular events for the diagnosis and prognosis of therapies. Therefore, the objective of this study was to analyze correlation between sociocultural, occupational, and lifestyle risk factors with levels of genetic instability in non-neoplastic cells of breast cancer patients. Total 150 individuals were included in the study that included 50 breast cancer patients submitted to chemotherapy (QT), 50 breast cancer patients submitted to radiotherapy (RT), and 50 healthy women without any cancer. Cytogenetic biomarkers for apoptosis and DNA damage were evaluated in samples of buccal epithelial and peripheral blood cells through micronuclei and comet assay tests. Elder age patients (61–80 years) had higher levels of apoptosis (catriolysis by karyolysis) and DNA damage at the diagnosis (baseline damage) with increased cell damage during QT and especially during RT. We also reported the increased frequencies of cytogenetic biomarkers in patients who were exposed to ionizing radiation as well as for alcoholism and smoking. QT and RT induced high levels of fragmentation (karyorrhexis) and nuclear dissolution (karyolysis) and DNA damage. Correlations were observed between age and karyorrhexis at diagnosis; smoking and karyolysis during RT; and radiation and karyolysis during QT. These correlations indicate that risk factors may also influence the genetic instability in non-neoplastic cells caused to the patients during cancer therapies

ATLANTIC EPIPHYTES: a data set of vascular and non-vascular epiphyte plants and lichens from the Atlantic Forest

Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts. Our work presents the first epiphyte data set with information on abundance and occurrence of epiphyte phorophyte species. All data compiled here come from three main sources provided by the authors: published sources (comprising peer-reviewed articles, books, and theses), unpublished data, and herbarium data. We compiled a data set composed of 2,095 species, from 89,270 holo/hemiepiphyte records, in the Atlantic Forest of Brazil, Argentina, Paraguay, and Uruguay, recorded from 1824 to early 2018. Most of the records were from qualitative data (occurrence only, 88%), well distributed throughout the Atlantic Forest. For quantitative records, the most common sampling method was individual trees (71%), followed by plot sampling (19%), and transect sampling (10%). Angiosperms (81%) were the most frequently registered group, and Bromeliaceae and Orchidaceae were the families with the greatest number of records (27,272 and 21,945, respectively). Ferns and Lycophytes presented fewer records than Angiosperms, and Polypodiaceae were the most recorded family, and more concentrated in the Southern and Southeastern regions. Data on non-vascular plants and lichens were scarce, with a few disjunct records concentrated in the Northeastern region of the Atlantic Forest. For all non-vascular plant records, Lejeuneaceae, a family of liverworts, was the most recorded family. We hope that our effort to organize scattered epiphyte data help advance the knowledge of epiphyte ecology, as well as our understanding of macroecological and biogeographical patterns in the Atlantic Forest. No copyright restrictions are associated with the data set. Please cite this Ecology Data Paper if the data are used in publication and teaching events. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ

Pharmacological Effects and Toxicogenetic Impacts of Omeprazole: Genomic Instability and Cancer

Omeprazole (OME) is commonly used to treat gastrointestinal disorders. However, long-term use of OME can increase the risk of gastric cancer. We aimed to characterize the pharmacological effects of OME and to correlate its adverse effects and toxicogenetic risks to the genomic instability mechanisms and cancer-based on database reports. Thus, a search (till Aug 2019) was made in the PubMed, Scopus, and ScienceDirect with relevant keywords. Based on the study objective, we included 80 clinical reports, forty-six in vitro, and 76 in vivo studies. While controversial, the findings suggest that long-term use of OME (5 to 40 mg/kg) can induce genomic instability. On the other hand, OME-mediated protective effects are well reported and related to proton pump blockade and anti-inflammatory activity through an increase in gastric flow, anti-inflammatory markers (COX-2 and interleukins) and antiapoptotic markers (caspases and BCL-2), glycoprotein expression, and neutrophil infiltration reduction. The reported adverse and toxic effects, especially in clinical studies, were atrophic gastritis, cobalamin deficiencies, homeostasis disorders, polyp development, hepatotoxicity, cytotoxicity, and genotoxicity. This study highlights that OME may induce genomic instability and increase the risk of certain types of cancer. Therefore, adequate precautions should be taken, especially in its long-term therapeutic strategies and self-medication practices

Mediatization of a (non-) preservation: the relations of society, journalism and the internet on the demolition of Monroe Palace

Tem sido uma constante no campo patrimonial a exortação de que as políticas do patrimônio precisam se aproximar dos anseios preservacionistas da população. Este artigo procura discutir essa máxima, analisando as razões para a demanda pró-preservação de não especialistas do Palácio Monroe, obra de arquitetura erigida pelo governo brasileiro em 1904, nos EUA, remontada no Brasil, em 1906, e demolida em 1976. Como forma de entender a percepção da sociedade sobre o patrimônio, procura-se mostrar como o processo de demolição do Monroe mobilizou a sociedade carioca. O objetivo é compreender a produção de memória e da história do Rio por pessoas que não pertencem às agências oficiais do patrimônio e que podem, como resultado, permitir que o circuito social da arquitetura seja incorporado às discussões do campo do patrimônio.Many scholars have pointed that the preservation policies should contemplate the society desires. This article discusses this maximum analyzing the reasons that produced demands from non-specialists about the preservation of the Monroe Palace. This building, that originally was built by the Brazilian government in 1904, in the US, was reassembled in Rio de Janeiro in 1906 and demolished in 1976. In order to understand the perception of society about this building, this paper seeks to show how the Monroe’s demolition mobilized Rio society. Taking this episode about the (non-) preservation of this architecture, we developed some reflections on the role of the journalism, blogs and websites, framed by one methodological preoccupation. The goal is to comprehend the production of the Rio’s memory and history by people that do not belong to official agencies of heritage in that city and, as result, to allow the discussion about the social circuit of the architecture within the heritage field